Longevity by Design

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Longevity by Design is your go-to podcast for unlocking the secrets to a longer, healthier life. Hosted by Dr. Gil Blander, a renowned scientist and entrepreneur in the fields of aging, nutrition, and personalized health, this show dives into cutting-edge research and practical strategies for optimizing your healthspan and lifespan.


In each episode, Dr. Blander sits down with leading longevity and health scientists to explore how we can live better, longer lives. From unpacking complex scientific concepts to sharing the latest advancements in aging research, Longevity by Design offers science-backed insights and actionable advice to help you add years to your life—and life to your years.


Dr. Blander is the founder and Chief Scientific Officer of InsideTracker, a healthspan company that leverages blood tests, DNA analysis, fitness tracker data, and other biomarkers to deliver personalized health recommendations. With a Ph.D. in biology from the Weizmann Institute of Science and postdoctoral research at MIT, Dr. Blander brings decades of expertise and passion to every conversation.


Tune in to Longevity by Design and discover how to live a longer, healthier, and more vibrant life.

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Recent Episodes
  • AI, LLMs & The Future of Longevity: Unlocking Healthspan Innovations with Dr. Eran Segal
    Apr 16, 2025 – 01:01:54
  • GLP-1, Wearables & Longevity: What You Need to Know – AMA with Gil & Ashley
    Apr 2, 2025 – 49:25
  • Muscle, Longevity, and the Power of Protein with Dr. Gabrielle Lyon
    Mar 19, 2025 – 01:18:38
  • The Science, Evolution, and Future of Lifespan and Healthspan with Dr. Michael Ringel
    Mar 5, 2025 – 01:12:52
  • How Long Can Humans Live? Insights from Dr. Jay Olshansky
    Feb 19, 2025 – 01:10:08
  • Precision Longevity Medicine with Dr. David Barzilai
    Feb 5, 2025 – 01:51:36
  • How Can a Nutrition AI Platform Help Us Live Healthier and Longer Lives with Dr. Dmitriy Richard Starson
    Jan 22, 2025 – 56:24
  • The Path to a 1,000-Year Lifespan with Dr. Aubrey de Grey
    Jan 8, 2025 – 53:55
  • Dietary Changes to Reduce the Risk of Prostate Cancer with Dr. John Erdman
    Dec 18, 2024 – 37:09
  • Unlocking Longevity: Dr. Jens Juul Holst on GLP-1’s Life-Changing Impact on Metabolic Health
    Dec 4, 2024 – 01:23:16
  • Food Fermentation and Its Effect on Healthspan with Dr. Jacob Allen and Dr. Mike Miller
    Nov 20, 2024 – 47:57
  • Taste and Smell Preferences and Their Impact on Health with Dr. Yanina Pepino
    Nov 6, 2024 – 01:01:46
  • Ask Me Anything (AMA): Nutrition Deep Dive with Dr. Gil Blander and Ashley Reaver
    Oct 23, 2024 – 22:39
  • Unlocking the Secrets of Longevity with Dr. David Sinclair
    Oct 9, 2024 – 46:23
  • The Impact of Artificial Intelligence, Machine Learning, and Large Language Models on Your Health and Wellness With Dr. Renee Deehan
    Sep 25, 2024 – 51:26
  • The Surprising Link Between Space Travel and Aging with Dr. David Furman
    Sep 11, 2024 – 01:08:34
  • Improvements in Blood and Fitness Tracker Biomarkers in a Digital Health Platform
    Aug 28, 2024 – 01:02:33
  • Parkinson's and Alzheimer's: The Gut-Brain Connection Explored with Dr. Julie Andersen
    Aug 15, 2024 – 01:14:00
  • The impact of ketones on performance and aging with Dr. Brianna Stubbs
    Jul 31, 2024 – 01:15:29
  • The impact of ultra-processed foods and fructose on metabolic health with Dr. Robert Lustig
    Jul 10, 2024 – 01:12:48
  • Ask Me Anything (AMA): Optimizing Health & Longevity with Dr. Gil Blander & Ashley Reaver, MS, RD, CSSD
    Jun 26, 2024 – 29:55
  • Understanding Aging to Extend Healthspan and Longevity with Dr. Gordon Lithgow
    Jun 12, 2024 – 48:50
  • The Impact of Exercise & Nutrition on Muscle, Tendons, Ligaments, & Aging with Dr. Keith Baar
    May 15, 2024 – 01:05:58
  • The Impact of DNA Damage & Lifestyle on Aging & Longevity Medicine with Dr. Morten Scheibye-Knudsen
    May 1, 2024 – 01:18:22
  • The Effects of Cellular Senescence and Senolytics on Healthspan with Dr. James Kirkland
    Apr 17, 2024 – 01:12:14
  • Aging, Mental Health, Suicide Risk & Prevention with Dr. Peter Franz
    Apr 3, 2024 – 39:15
  • XPRIZE Healthspan: Revolutionizing Human Aging & Healthspan with Dr. Jamie Justice
    Mar 20, 2024 – 01:07:49
  • Longevity Genes, Blood Biomarkers of Aging, & Targeting Aging with Metformin with Dr. Nir Barzilai
    Mar 6, 2024 – 01:19:26
  • The Impact of Exercise on Blood Biomarkers and InsideTracker’s New DNA Healthspan Report with Dr. Bartek Nogal
    Feb 21, 2024 – 39:49
  • Ask Me Anything (AMA): Oral Health, Healthspan, and Longevity with Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD
    Feb 7, 2024 – 55:45
  • How Our Blood Impacts Brain Aging and Alzheimer’s Disease with Dr. Tony Wyss-Coray
    Jan 24, 2024 – 01:21:44
  • Do NAD Analogs and Resveratrol Boost Cellular Health and Longevity With Dr. Joe Baur
    Jan 10, 2024 – 01:11:19
  • The Latest Updates in Longevity Research with Dr. Eric Verdin
    Dec 13, 2023 – 01:06:04
  • How To Be Smarter About Protein Intake With Dr. Nick Burd
    Nov 29, 2023 – 01:03:25
  • Tracking Your Body’s Data to Improve Health Outcomes with Dr. Sara Gottfried
    Nov 15, 2023 – 01:22:55
  • Ask Me Anything: Lowering Cholesterol and Optimizing VO2max
    Oct 25, 2023 – 01:24:46
  • How to Improve Your Healthspan Using DNA Insights with Dr. Bartek Nogal
    Oct 11, 2023 – 01:12:39
  • Neurosurgery, Preventing Alzheimer’s Disease, and Optimizing VO2max with Dr. Joseph Maroon
    Sep 27, 2023 – 01:16:46
  • How GLP-1 Agonists Are Changing Obesity Care with Dr. Spencer Nadolsky
    Sep 13, 2023 – 01:13:08
  • Insulin Resistance, Weight Management, and Eating Optimally with Dr. Mitch Roslin
    Aug 23, 2023 – 55:05
  • How Hyperbaric Oxygen Therapy improves cognition with Dr. Shai Efrati
    Aug 9, 2023 – 01:03:17
  • Using Synthetic Biology To Extend Lifespan With Dr. Nan Hao
    Jul 26, 2023 – 01:01:23
  • How To Prevent And Reverse Insulin Resistance with Dr. Jennifer Lovejoy
    Jul 12, 2023 – 01:20:56
  • Dr. Jennifer Lovejoy—How Hormone Balance and Optimal Metabolism Promote Healthy Aging
    Jun 21, 2023 – 01:08:32
  • Dr. John Oliffe—Overlooking Men’s Mental Health: A Threat To Longevity
    Jun 7, 2023 – 01:03:17
  • Dr. Emma Teeling—DNA Repair Mechanisms and Aging: Lessons From Bats
    May 24, 2023 – 01:08:18
  • Dr. Renee Deehan—Why Everyone Should Care About Women’s Health
    May 10, 2023 – 01:29:30
  • Dr. Leroy Hood + Dr. Nathan Price—How Assessing Biological Age Improves Wellness
    Apr 26, 2023 – 01:24:37
  • Dr. Rachele Pojednic—How Exercise Improves Healthspan
    Apr 12, 2023 – 55:47
  • Dr. Kate Wolin—How To Use Behavioral Science To Build Healthy Habits
    Mar 29, 2023 – 01:38:23
Recent Reviews
  • Don-healthy at 65
    Excellent podcast!
    I have been using Inside Tracker since 2021 which is giving me absolute control over my health by knowing exactly what the status of my bio markers are and how they are trending. This podcast is the perfect companion for those who want to be up-to-date on the latest scientific research on healthy aging and longevity in a way that every day people can understand. Great job and keep up the good work!
  • HealthySpainaird
    Great resource!
    This is a very informative podcast. I have always had a fear of dying so figuring out how to live better for longer has always been a goal of mine. I especially enjoyed the episode with Eran Segal!
  • Sanediertybirt
    Great stuff
    Love it
  • Granted27
    Mostly helpful
    As with so many health related podcasts, these guests get really deep in the weeds really quickly. For the smart layperson, this is not helpful. The recent podcast on protein was supposed to be about how to add more protein to ones diet. That is not what the conversation ended up being. It was about high level athletes and when they should eat their protein. Would have been more helpful to actually discuss the topic of the title. Generally helpful but needs some work.
  • nhastingsk
    Best podcast on longevity and health!
    I listened to this after a visit w my 91 year old aunt who is committed to walking, yoga and nutrition (a retired nurse). She and I are both enjoying the podcast now. Although we don’t understand some of the terminology, (we’d rather that be the case than lame & trite simplicity) we have learned a lot and both feel inspired to have “life in our years!” We have not heard such evidence-based and credible information that everyone can benefit from. Thank you and please continue your great work bringing knowledgeable guests for distribution to those interested in healthy lives.
  • Optimistic follower
    Bravo!
    As a 77 year old woman who exercises, eats plant forward with fish, some eggs, and longevity in both parents, I find this podcast fascinating. Given I was raised by older people, who were healthy (both Lithuanian), I am trying to match their ages( 93 and 97)and then die quickly. The science and latest research here is so important because older people are very different— profound changes are occurring. The medical profession ignores this, in general. I look to the blue zones, and want to spread them to Santa Barbara California.
  • SWAT Doc
    Strongly science-based and reliable information
    The Longevity by Design Podcast really suprised me. I am a medical doctor specializing in functional medicine and have come to realize that most new podcasts I come across in the consumer health space are short on scientific evidence and long on anecdoctal advice. That along with the fact that often the podcast hosts may not be experts in the subject matter of their own podcast. This podcast completely upends that trend! The LbD Podcast is strongly science-based and they attract some of the top scientists and doctors in the fields of anti-aging and longevity. I do not sense any inherent biases here in the information being presented. Certainly the podcast hosts are proponents of an individual taking action in the interests of their own health, which could, and rightfully, should include a full set of biomarkers which is their sponsoring company offers. I enjoy the banter between the hosts and their guests as they get to know each other and what compelled them into their respective fields of study. The discussions can become very nuanced and deep, but the take home points are clearly drawn and spoken understandably.
  • maurabv
    Great Info, Many Skips in Podcast
    I listened to my first episode of this podcast (Dr. Roger Fielding) and overall it was great content, but very frustrating that there were several skips during some of the most relevant sections. I thought at first it was due to something happening on my devices but after going back to try and listen again, I realized there was some sort of technical glitch with the podcast. I’ll try another episode and see how it goes.
  • jtmyatt$&@
    Great content and guests, production could be improved
    Please improve the splicing of audio. I appreciate the removal of extra content, but the clipping and unnatural transitions are distracting.
  • Eatpraylovenc
    From the science lab directly to mainstream
    In a world where anything on the internet is deemed accurate without fact checking, it’s profoundly necessary to have the scientists detailing exactly what they have learned and where the science is headed. I love the stories from the lab, sheds light on the scientific community.
  • love_psych
    Incredible company, incredible podcast
    Dr. Gil Blander is insightful and interesting. Thank you for providing this resource! Everyone who cares about their mind and their body should listen.
  • franknobeans
    Loving these conversations
    This podcast is pulling some seriously fascinating interviews. The episode with David Katz makes my heart all aflutter with optimism as a public health professional. More conversations like these, please!!
  • jcowcool
    Worth a listen
    This podcast was thought provoking from start to finish. Sharing with my network!!
  • dalicalzi
    Excellent Podcast!
    I’m an avid listener of longevity-focused podcasts and this podcast has moved to the top of my list. The David Katz (episode 2) one is superb - every health professional and anyone interested in health should listen to this episode. I’m patiently waiting for when the next episode will come out. Highly recommend!
  • BTE87
    Very informative
    This podcast is very informative and has true experts and science-backed data to back up the information they’re sharing. Hard to find this day and age.
  • shellydar
    Incredible podcast by trusted experts
    Longevity by Design is an engaging podcast hosted by experts in the field of aging. The conversations with world renowned experts are inspiring!
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